HuagongsheHuagongshe Chemistry Print Report · For research reference only
Mannitol → 1,2:5,6-Di-O-isopropylidene-D-mannitol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Mannitol | HCID 6251 | — |
| Reactant | HCID 88306345 | HCID 88306345 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1,2:5,6-Di-O-isopropylidene-D-mannitol | HCID 96011 | — |
Reaction Steps
In the preparation of the diketonide deriving from D-mannitol acetone is the ketone which is preferentially used. Then, the 1,2,5,6-diacetone D-mannitol is prepared by reacting acetone, to which solid zinc chloride has been added, with D-mannitol with stirring within a temperature range of from 0° C. to +50° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04413142 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-d50c5cfb9ad14af39c5720aa3c0be4ce |
| Source note | uspto-grants-1983_11 |