HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → 2-Bromo-4-fluorophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromo-4-fluorophenol | HCID 605472 | — |
Reaction Steps
At -20° C., 15.3 ml of bromine is dripped into 33.6 g of 4-fluorophenol in 300 ml of dichloromethane. After the solution has stood for 24 hours it is colorless. Distillation gives 46 g of 2-bromo-4-fluorophenol of boiling point 70° C./13.3 mbars.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04414208 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-922d7c90abd24434a1a4a517ee4e1002 |
| Source note | uspto-grants-1983_11 |