Sodium Hydroxide → HCID 178515404, compound

Participants

Reaction Steps

To 3.5 g (0.0132 mole) of 1,2,3,4-tetrahydro-1-hydroxy-1-[1-(1,2,4-triazolyl)methyl]-naphthalene hydrochloride in 200 ml of water is added 2.0 g (0.025 mole) of 50% NaOH, and the mixture is stirred. The organic material is extracted 2×100 ml of ether, and the extract is washed 2×50 ml of water, dried over anhydrous magnesium sulfate, and concentrated to give 2.6 g (85.9%) of the product, mp 105°-8°.

Provenance & Evidence