反应详情

The product of stage (b) (3.0 g) and sodium methoxide (0.57 g) were dissolved in methanol (75 ml) and treated with methyl iodide (1.3 g). After standing for 3 days the solution was evaporated to dryness, treated with water and extracted into dichloromethane. The extract was washed with water and dried. Evaporation yielded 0.8 g of a solid, mp 82°-85° C., which was recrystallised twice from petroleum ether (80°-100°).

1. customthe solution was evaporated to dryness
2. additiontreated with water
3. extractionextracted into dichloromethane
4. washThe extract was washed with water
5. customdried
6. customEvaporation