Benzyl chloroformate → Benzyl-4-chloro-5-formyl-2,3,6,7-tetrahydro-1H-1-azepinecarboxylate

HRID 1648927Notes

Reaction equation

HRID 1648927 reaction equation
C([N:8]1[CH2:14][CH2:13][C:12]([CH:15]=[O:16])=[C:11]([Cl:17])[CH2:10][CH2:9]1)C1C=CC=CC=1.Cl[C:19]([O:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:20]>>[CH2:22]([O:21][C:19]([N:8]1[CH2:14][CH2:13][C:12]([CH:15]=[O:16])=[C:11]([Cl:17])[CH2:10][CH2:9]1)=[O:20])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 10387Benzyl chloroformateHCID 130720301-benzyl-5-chloro-2,3,6,7-tetrahydro-1H-azepine-4-carbaldehyde

Product 1

HCID 20481342Benzyl-4-chloro-5-formyl-2,3,6,7-tetrahydro-1H-1-azepinecarboxylate

Procedure

This compound was prepared from 40 gm (0.16 mol) of 1-benzyl-4-chloro-5-formyl-2,3,6,7-tetrahydro-1H-azepine and 34.2 gm (0.20 mol) of benzyl chloroformate analogous to Example G.

Sources & evidence

ORD record
ord-9a536298f3804d7b81bbb6000fdb9057
Source dataset
uspto-grants-1983_11
Patent number
US04414225

Reaction notes

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