HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl 5-formyl-2(S)-phthalimidopentanoate → 5-Formyl-2(S)-phthalimidopentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl 5-formyl-2(S)-phthalimidopentanoate | HCID 11003033 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | 5-Formyl-2(S)-phthalimidopentanoic acid | HCID 13241633 | 102.4% |
Reaction Steps
Benzyl 5-formyl-2(S)-phthalimidopentanoate (4.72 g) was dissolved in 230 ml of ethyl acetate and hydrogenated at 5 psig of hydrogen over 0.82 g of 10% palladium on carbon. After the uptake of 1 equivalent of hydrogen, catalyst was removed by filtration. Removal of solvent afforded 3.64 g of 5-formyl-2(S)-phthalimidopentanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04415496 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-5d66d6bf0aef461ab462a956cb4b14f0 |
| Source note | uspto-grants-1983_11 |