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HRID1649057

反应详情

EQUATION

反应方程式

HRID 1649057 的结构方程式

REACTANTS

反应物

1
结构：O=CCCC[C@@H](C(=O)OCc1ccccc1)N1C(=O)c2ccccc2C1=O
HCID11003033

未命名化合物

PRODUCTS

生成物

1
结构：O=CCCC[C@@H](C(=O)O)N1C(=O)c2ccccc2C1=O
HCID13241633

未命名化合物

收率 102.4%

AUXILIARIES

试剂、催化剂与溶剂

3
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

结构：[H][H]
溶剂HCID178418361

未命名化合物

2 次

PROCEDURE

实验过程

Benzyl 5-formyl-2(S)-phthalimidopentanoate (4.72 g) was dissolved in 230 ml of ethyl acetate and hydrogenated at 5 psig of hydrogen over 0.82 g of 10% palladium on carbon. After the uptake of 1 equivalent of hydrogen, catalyst was removed by filtration. Removal of solvent afforded 3.64 g of 5-formyl-2(S)-phthalimidopentanoic acid.

WORKUP

后处理

  1. customRemoval of solvent