2-Methylimidazoline → 1-[(2-Ethyl-6-methylphenyl)carbamoylmethyl]-2-methyl-2-imidazoline

HRID 1649147Notes

Reaction equation

HRID 1649147 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH2:13][CH3:14])=[O:4].[CH3:15][C:16]1[NH:20][CH2:19][CH2:18][N:17]=1>[N+](C)([O-])=O>[CH2:13]([C:7]1[CH:8]=[CH:9][CH:10]=[C:11]([CH3:12])[C:6]=1[NH:5][C:3]([CH2:2][N:20]1[CH2:19][CH2:18][N:17]=[C:16]1[CH3:15])=[O:4])[CH3:14]

Participants

4

Reactant 2

HCID 107982-MethylimidazolineHCID 6704772-Chloro-N-(2-ethyl-6-methylphenyl)acetamide

Product 1

HCID 204806291-[(2-Ethyl-6-methylphenyl)carbamoylmethyl]-2-methyl-2-imidazoline

Reagents, catalysts & solvents 1

HCID 6375NitromethaneSolvent

Procedure

In a manner similar to Ex. IA react 21.17 gm. (0.1 M) of 2-chloro-2'-ethyl-6'-methylacetanilide and 42.1 gm. (0.5 M) of lysidine in 250 ml. of nitromethane, to obtain the title compound:

Workup

  1. customIA react 21.17 gm

Sources & evidence

ORD record
ord-ebadf92091954d07bc961a360782ae85
Source dataset
uspto-grants-1983_11
Patent number
US04415587

Reaction notes

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