HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 8-Aminoquinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 13317110 | HCID 13317110 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 8-Aminoquinolin-2(1H)-one | HCID 13317112 | 91.1% |
Reaction Steps
8-Acetylaminocarbostyril (21.5 g, 0.106 mol) was suspended in 190 ml of 20% hydrochloric acid and the suspension was stirred while heating under reflux for 1 hour. The reaction mixture was poured into ice water and neutralized with 5 N sodium hydroxide. Crystals which formed were collected by filtration to give 15.47 g of 8-aminocarbostyril.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04415572 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-6d38258e6bc741be942b36a5bb376208 |
| Source note | uspto-grants-1983_11 |