2,3,6-Trichlorobenzaldehyde → 2-(2,3,6-Trichlorobenzylidene)-3-oxo-4-chlorobutyric acid ethyl ester

HRID 1649408Notes

Reaction equation

HRID 1649408 reaction equation
[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[C:6]([Cl:11])[C:3]=1[CH:4]=O.[CH2:12]([O:14][C:15](=[O:21])[CH2:16][C:17]([CH2:19][Cl:20])=[O:18])[CH3:13]>>[CH2:12]([O:14][C:15](=[O:21])[C:16](=[CH:4][C:3]1[C:6]([Cl:11])=[CH:7][CH:8]=[C:9]([Cl:10])[C:2]=1[Cl:1])[C:17](=[O:18])[CH2:19][Cl:20])[CH3:13]

Participants

3

Reactant 2

HCID 207812,3,6-TrichlorobenzaldehydeHCID 69484Ethyl 4-chloroacetoacetate

Product 1

HCID 540808822-(2,3,6-Trichlorobenzylidene)-3-oxo-4-chlorobutyric acid ethyl ester

Procedure

210 g of 2,3,6-trichlorobenzaldehyde were reacted with 4-chloroacetoacetic acid ethyl ester as described in Example 43. 213 g of a 3:1 isomer mixture were obtained as an oily crude product.

Sources & evidence

ORD record
ord-9559a8732e31499a8b565458810d3082
Source dataset
uspto-grants-1983_11
Patent number
US04416880

Reaction notes

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