Hydrochloric Acid → HCID 20479683, compound

Participants

Reaction Steps

3.8 g of 8-(1-piperazinyl)-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid hydrochloride was added to 100 ml of water and 1 N aqueous sodium hydroxide solution was added thereto followed by heating the mixture to form a uniform solution. The solution was rendered alkaline (pH=8) with dilute hydrochloric acid to obtain 3.1 g of 8-(1-piperazinyl)-5-methyl-6,7-dihydro-1H,5H-benzo[ij]quinolizine-2-carboxylic acid as colorless needles having a melting point of 264° to 265° C.

Provenance & Evidence