Hydrochloric Acid → HCID 131713236, compound

Participants

Reaction Steps

A mixture of 1,3-difluoro-2-tert.butoxycarbonylamino-4-phthalimidobutane (0.1 g, 0.27 mmol) obtained as in Step C above and concentrated hydrochloric acid is heated at 100° C. for 48 hours. The solvent is evaporated in vacuo and the residue is taken up in water. Insoluble phthalic acid is filtered off and the filtrate concentrated to yield 1,3-difluoro-2,4-diaminobutane, dihydrochloride (0.03 g).

Provenance & Evidence