Acetic Anhydride → HCID 19854190, compound

Participants

Reaction Steps

A solution of 4-(4-fluorophenyl)cyclohexane-1,3-dione (4 g), acetic anhydride (6 ml) and 4-(N,N-dimethylamino) pyridine (0.2 g) in toluene (50 ml) was refluxed 3 hours. Evaporation of the toluene in vacuo gave a red oil, which, after purification on a silica gel column using 5% (v/v) diethyl ether-methylene chloride as eluant, gave the title compound as a yeoolw solid (4 g) of m.p. 67°-68° C.

Provenance & Evidence