3-(4-Fluorobenzoyl)butanoic acid → 3-[4-[4-(3-phthalimidopropyl)-1H-imidazol-1-yl]benzoyl]-butyric acid

Participants

Reaction Steps

Prepared by a method analogous to that of Example (a) from 2.6 g (10.2 mmol) of 4-(3-phthalimidopropyl)-imidazole and 2.2 g (10.5 mmol) of 3-(4-fluorobenzoyl)-butyric acid. 3.4 g (75%) of a brownish, viscous oil is obtained which is used without further purification for the next stage.

Provenance & Evidence