HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminum(III) Chloride → 3-[4-(3-Phthalimidopropyl)benzoyl]-butyric acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 2-(3-Phenyl-propyl)-isoindole-1,3-dione | HCID 7663529 | — |
| Reactant | Methyl 4-chloro-3-methyl-4-oxobutanoate | HCID 14403282 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 3-[4-(3-Phthalimidopropyl)benzoyl]-butyric acid methyl ester | HCID 54211140 | — |
Reaction Steps
8.2 g (50 mmol) of 3-methoxycarbonyl-2-methyl-propionic acid chloride and 13.3 g (50 mmol) of 3-phthalimidopropyl-benzene are reacted with 26 g of aluminum chloride in 1,2-dichloroethane analogously to Example 4(a). The oil obtained crystallizes from ethanol as beige coloured crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04921856 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-bd00b93da7974a9d88bd09892c4de700 |
| Source note | uspto-grants-1990_05 |