Dichloromethane → Trifluoroacetic acid

HRID 164986Notes

Reaction equation

HRID 164986 reaction equation
[CH:1]1([c:4]2[c:5]([N:22]3[CH2:23][CH2:24][N:25]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:26][CH2:27]3)[c:6]3[c:7]([n:8][cH:9]2)[n:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[n:11][cH:12]3)[CH2:2][CH2:3]1.[Cl:42][CH2:43][Cl:44].[F:35][C:36]([C:37](=[O:38])[OH:39])([F:40])[F:41]>>[CH:1]1([c:4]2[c:5]([N:22]3[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]3)[c:6]3[c:7]([n:8][cH:9]2)[n:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[n:11][cH:12]3)[CH2:2][CH2:3]1.[F:35][C:36]([C:37](=[O:38])[OH:39])([F:40])[F:41]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 68758042tert-butyl 4-(5-cyclopropyl-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

Product 2

HCID 6422Trifluoroacetic acidHCID 687612645-Cyclopropyl-1-[(4-methoxyphenyl)methyl]-4-piperazin-1-ylpyrazolo[3,4-b]pyridine

Sources & evidence

ORD record
ord-04503d93ef2c48848b8167f6d1e6e29f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…