Water → HCID 178485846, compound

HRID 1649879Notes

Reaction equation

HRID 1649879 reaction equation
[NH2:1][C:2]1[NH:6][N:5]=[N:4][N:3]=1.[CH3:7][N:8]=[C:9]=[O:10].O>CN(C=O)C>[CH3:7][NH:8][C:9](=[O:10])[NH:1][C:2]1[NH:6][N:5]=[N:4][N:3]=1

Participants

5

Reactant 3

HCID 962WaterHCID 12228Methyl IsocyanateHCID 178509299HCID 178509299, compound

Product 1

HCID 178485846HCID 178485846, compoundYield 89.8%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
100 °C

Procedure

5-Aminotetrazole (5.5 g, 0.065 mole) was dissolved in 75 ml of DMF. On the addition of methylisocyanate (5 g) the temperature began to slowly rise to 40° C. with the formation of a white solid. The solution was heated for 90 minutes at 100° C. and on cooling, poured into cold water. The resulting white solid was filtered, water washed and dried to give 8.3 g of product which softened at 264°-267° C. but was not melted completely at 305° C.

Workup

  1. customto slowly rise to 40° C. with the formation of a white solid
  2. temperatureon cooling
  3. filtrationThe resulting white solid was filtered
  4. washwater washed
  5. customdried

Sources & evidence

ORD record
ord-e765215cf6c1447da57be778229a93fd
Source dataset
uspto-grants-1990_05
Patent number
US04921965

Reaction notes

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