HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 5-Amino-1-hydroxy-5,6,7,8-tetrahydro-naphthalene hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 5-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride | HCID 70349932 | — |
| Product | 5-Amino-1-hydroxy-5,6,7,8-tetrahydro-naphthalene hydrobromide | HCID 19855451 | 80% |
Reaction Steps
0.15 mol of 5-amino-1-methoxy-5,6,7,8-tetrahydronaphthalene hydrochloride is heated at a bath temperature of 125° C. in 75 ml of aqueous 48% strength HBr for 3 hours. The mixture is evaporated, the residue is dissolved in a little ethanol and the products are precipitated as the hydrobromides by addition of ether. Yield: 80% of theory; melting point: 152° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04921998 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-ecb9f35df730436fa83e64da16c2b12d |
| Source note | uspto-grants-1990_05 |