Hydrochloric Acid → HCID 19855554, compound

Participants

Reaction Steps

A mixture of 0.3 g (1.2 mmoles) of 1-(N-ethyl-acetamido)-2-(2,6-dimethylphenyl-amino)-propane and 5 ml of a 20% aqueous hydrochloric acid solution is boiled for 3 hours. The solvent is evaporated, and the residue is dissolved in 30 ml of water. The solution is washed five times with 5 ml of chloroform, each, and then the solvent is evaporated. The residue is crystallized from a mixture of chloroform and diethyl ether to obtain 0.14 g (56%) of 1-ethylamino-2-(2,6-dimethylphenyl-amino)-propane dihydrochloride; m.p.: 155°-157° C.

Provenance & Evidence