Benzyl Chloride → (3-Vinylphenyl)phenylmethane
Reaction equation
[CH2:1](Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:9]([C:11]1[CH:12]=[C:13]([Mg]Br)[CH:14]=[CH:15][CH:16]=1)=[CH2:10]>>[CH:9]([C:11]1[CH:12]=[C:13]([CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH:14]=[CH:15][CH:16]=1)=[CH2:10]Participants
3
Procedure
The method using benzyl chloride as a starting material is described. Benzyl chloride is reacted with a Grignard reagent of 3-vinylphenylmagnesium bromide in the presence of dichlorodiphosphine nickel complex catalyst to obtain (3-vinylphenyl)phenylmethane. The reaction temperature using Grignard reagent is in the range of 10° to 80° C. and the use quantity of Grignard reagent is 1.0 to 1.2 equivalent to 1 mole of benzyl chloride. ##STR8##
Sources & evidence
- ORD record
- ord-08e16c81b8a3422796d0dce2f123f552
- Source dataset
- uspto-grants-1990_05
- Patent number
- US04922052
Reaction notes
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