反应详情

A solution of 25 g. (0.138 mmole) of 2-(2-bromoethyl)-1,3-dioxolane and 36.2 g. (0.138 mmole) of triphenylphosphine in 30 ml. of toluene was heated at 100° C. for 18 hours. The reaction was cooled to yield two phases. The toluene phase was decanted and the oil remaining crystalized at -78° C. in ethyl acetate. Decantation of the ethyl acetate and warming of the crystals to room temperature gave an oil. The oil was dried under vacuum (0.05 torr) at 100° C. for 16 hours to yield 15 g. (27%) of the title compound as a solid glass which was ground to a powder.

1. temperatureThe reaction was cooled
2. customto yield two phases
3. customThe toluene phase was decanted
4. customthe oil remaining crystalized at -78° C. in ethyl acetate
5. customgave an oil
6. customThe oil was dried under vacuum (0.05 torr) at 100° C. for 16 hours
7. customto yield 15 g