Ethanol → HCID 14608785, compound

Participants

Reaction Steps

A mixture of 0.38 g of ethyl 8-fluoro-9-(4-methyl-1-piperazinyl)-6-oxo-6H-benzo[c]quinolizine, 25 ml of 0.1N sodium hydroxide and 5 ml of ethyl alcohol was refluxed for 18 hours. The mixture was cooled to room temperature and the pH adjusted to 6 with acetic acid. Most of the volatiles were removed under vacuum to give 0.31 g of water washed and dried desired product, mp 264°-266° C.

Provenance & Evidence