1-Tetralone → HCID 19595604, 화합물

HRID 1650362노트

반응식

HRID 1650362 반응식
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH2:12]1[CH2:22][C:20](=[O:21])[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:13]1.C([O-])(O)=O.[Na+]>C(Cl)(Cl)Cl>[O:21]1[C:20]2[CH:22]=[CH:12][CH:13]=[CH:14][C:19]=2[CH:18]=[CH:17][CH2:16][C:15]1=[O:9]

참가 물질

5

반응물 3

HCID 107241-TetraloneHCID 70297m-Chloroperbenzoic acidHCID 516892Sodium Bicarbonate

생성물 1

HCID 19595604HCID 19595604, 화합물

시약·촉매·용매 1

HCID 6212Chloroform용매2회

실험 절차

To 100 g of m-chloroperbenzoic acid in 1 l of chloroform at 0° C. is added dropwise 100 g of α-tetralone in 250 ml chloroform. After 5 days of stirring at room temperature the reaction mixture is treated carefully with 1 l sat. NaHCO3 and stirred for 1/2 hour. The organic layer is separated, washed with 500 ml of water and solid NaHCO3 until no evolution of gas. The organic layer is separated washed with sat. NaHCO3 and water and dried (MgSO4) After filtering and concentrating to dryness it is vaccum distilled to obtain low melting material which is used directly in the next step.

후처리

  1. stirringstirred for 1/2 hour
  2. customThe organic layer is separated
  3. washwashed with 500 ml of water and solid NaHCO3 until no evolution of gas
  4. customThe organic layer is separated
  5. washwashed with sat. NaHCO3 and water
  6. dry with materialdried (MgSO4)
  7. filtrationAfter filtering
  8. concentrationconcentrating to dryness it
  9. distillationis vaccum distilled
  10. customto obtain low melting material which

출처 및 근거

ORD 기록
ord-3be0fd0cb60e401699672c68d7cdf4f6
출처 데이터셋
uspto-grants-1990_05
특허 번호
US04924010

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