1-Bromohexane → Ethyl 2-[(hexyloxy)imino]-3-oxobutanoate

HRID 1650447Notes

Reaction equation

HRID 1650447 reaction equation
[OH:1][N:2]=[C:3]([C:9](=[O:11])[CH3:10])[C:4]([O:6][CH2:7][CH3:8])=[O:5].C(=O)([O-])[O-].[K+].[K+].[CH2:18](Br)[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[CH2:18]([O:1][N:2]=[C:3]([C:9](=[O:11])[CH3:10])[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

Participants

4

Reactant 3

HCID 81011-BromohexaneHCID 11430Potassium CarbonateHCID 178472877HCID 178472877, compound

Product 1

HCID 53879425Ethyl 2-[(hexyloxy)imino]-3-oxobutanoateYield 99.5%

Procedure

Ethyl 2-hydroxyimino-3-oxobutyrate (syn isomer, 40 g.), N,N-dimethylformaide (200 ml.), potassium carbonate (52 g.) and n-hexyl bromide (41.4 g.) were treated in a similar manner to that of Example F-(1) to give ethyl 2-n-hexyloxyimino-3-oxobutyrate (syn isomer, 60.7 g.) oil.

Sources & evidence

ORD record
ord-6d10e0022a604578bac9b18a2ec99ac4
Source dataset
uspto-grants-1990_05
Patent number
US04923998

Reaction notes

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