Imidazole → Benzyl (1r,4r)-4-(tert-butyldimethylsilyloxy) cyclohexylcarbamate
Reaction equation
[C:24]([CH3:25])([CH3:26])([CH3:27])[Si:28]([CH3:29])([CH3:30])[Cl:31].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([NH:10][CH:11]1[CH2:12][CH2:13][CH:14]([OH:17])[CH2:15][CH2:16]1)=[O:18].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[nH:19]1[cH:20][cH:21][n:22][cH:23]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([NH:10][CH:11]1[CH2:12][CH2:13][CH:14]([O:17][Si:28]([C:24]([CH3:25])([CH3:26])[CH3:27])([CH3:29])[CH3:30])[CH2:15][CH2:16]1)=[O:18]Participants
5
Sources & evidence
- ORD record
- ord-b39aa2ea57bf49f88115a25a3f58ece7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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