Water → HCID 54452095, compound

HRID 1650590Notes

Reaction equation

HRID 1650590 reaction equation
[OH2:1].[OH-].[Na+].Cl[C:5]1([CH2:8][C:9]([CH2:11][C:12]2([Cl:15])[CH2:14][CH2:13]2)=O)[CH2:7][CH2:6]1.[Cl:16][C:17]1C=CC(C=O)=[CH:19][CH:18]=1>C(O)C>[Cl:16][C:17]1[CH:6]=[CH:7][C:5]([CH:8]=[CH:9][C:11]([C:12]2([Cl:15])[CH2:13][CH2:14]2)=[O:1])=[CH:19][CH:18]=1

Participants

6

Reactant 4

HCID 962WaterHCID 77264-ChlorobenzaldehydeHCID 14798Sodium HydroxideHCID 54383938HCID 54383938, compound

Product 1

HCID 54452095HCID 54452095, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

50 ml of water and 10 pellets of solid sodium hydroxide are added at room temperature to a mixture of 60 g (0.5 mol) of 1-chlorocyclopropylmethyl ketone, 70 g (0.5 mol) of 4-chlorobenzaldehyde and 250 ml of ethanol. The mixture is stirred at room temperature for 16 hours. The precipitated solid is then filtered off with suction. In this manner, 108.5 g (89% of theory) of 1-chlorocyclopropyl 4-chlorophenyl-ethenyl ketone are obtained in the form of a solid substance of melting point 92° C.

Workup

  1. filtrationThe precipitated solid is then filtered off with suction

Sources & evidence

ORD record
ord-8dcc0e5050c9460bb025698e8860c9d6
Source dataset
uspto-grants-1990_05
Patent number
US04925482

Reaction notes

Loading…