Water → HCID 53893725, compound

HRID 1650592Notes

Reaction equation

HRID 1650592 reaction equation
O.[OH-].[Na+].[CH3:4][C:5]([C:7]1([S:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:9][CH2:8]1)=[O:6].[Cl:17][C:18]1[CH:25]=[CH:24][C:21]([CH:22]=O)=[CH:20][CH:19]=1>C(O)C>[C:11]1([S:10][C:7]2([C:5]([CH:4]=[CH:22][C:21]3[CH:24]=[CH:25][C:18]([Cl:17])=[CH:19][CH:20]=3)=[O:6])[CH2:9][CH2:8]2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

6

Reactant 4

HCID 962WaterHCID 77264-ChlorobenzaldehydeHCID 14798Sodium HydroxideHCID 14348393HCID 14348393, compound

Product 1

HCID 53893725HCID 53893725, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

50 ml of water and 8 pellets of solid sodium hydroxide are added at room temperature to a mixture of 75 g (0.39 mol) of 1-phenylmercaptocyclopropyl methyl ketone, 56 g (0.39 mol) of 4-chlorobenzaldehyde and 200 ml of ethanol. The mixture is stirred at room temperature for 14 hours. The precipitated solid is then filtered off with suction. In this manner, 120.3 g (98% of theory) of 4-chlorophenyl-ethenyl 1-phenylmercapto-cyclopropyl ketone are obtained in the form of a solid substance.

Workup

  1. filtrationThe precipitated solid is then filtered off with suction

Sources & evidence

ORD record
ord-576d33fd0703419885f3408eb81e53e6
Source dataset
uspto-grants-1990_05
Patent number
US04925482

Reaction notes

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