HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminum(III) Chloride → 2,3-Difluoro-4-hydroxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 4-Ethoxy-2,3-difluorobenzonitrile | HCID 14495626 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2,3-Difluoro-4-hydroxybenzonitrile | HCID 2736978 | — |
Reaction Steps
A mixture of 0.1 mole of 4-ethoxy-2,3-difluorobenzonitrile, 0.12 mole of aluminium chloride and 150 ml of toluene is heated at the boil for 2 hours. Working up in the customary manner gives the phenol in the form of a colourless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04925590 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-20bbd3a5e7904b6f80e89768b5c955af |
| Source note | uspto-grants-1990_05 |