Thionyl Chloride → HCID 19762694, compound

HRID 1650618Notes

Reaction equation

HRID 1650618 reaction equation
[CH3:1][C:2]1([C:8]2[CH:9]=[C:10]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:11](O)=[O:12])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.S(Cl)([Cl:21])=O>>[CH3:1][C:2]1([C:8]2[CH:9]=[C:10]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:11]([Cl:21])=[O:12])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 18371174HCID 18371174, compound

Product 1

HCID 19762694HCID 19762694, compoundYield 100%

Procedure

1.24g (5 mmoles) of 3-(1-methylcyclohexyl)-4-methoxybenzoic acid and 15 ml of thionyl chloride are heated at reflux until the cessation of gas evolution. The reaction mixture is evaporated to dryness. 1.32 g (100% yield) of crude 3-(1-methylcyclohexyl)-4-methoxybenzoic acid chloride which is used as such for the following synthesis are obtained.

Workup

  1. temperatureat reflux until the cessation of gas evolution
  2. customThe reaction mixture is evaporated to dryness

Sources & evidence

ORD record
ord-f675b0cadf4040afaee461fe293f2b57
Source dataset
uspto-grants-1990_05
Patent number
US04925658

Reaction notes

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