Bicarbonate Ion → 4-benzyl-3-[1-benzyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl]-1,3-oxazolidin-2-one
Reaction equation
[C:49](=[O:50])([O-:51])[OH:52].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[N:9]([C:14]([CH:15]=[CH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]2)=[O:25])[C:10](=[O:13])[O:11][CH2:12]1.[CH3:26][O:27][CH2:28][N:29]([CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[CH2:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[Cl:54][CH2:55][Cl:56].[Na+:53].[OH:42][C:43]([C:44]([F:45])([F:46])[F:47])=[O:48]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[N:9]([C:14]([CH:15]2[CH:16]([c:17]3[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]3)[CH2:30][N:29]([CH2:35][c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[CH2:28]2)=[O:25])[C:10](=[O:13])[O:11][CH2:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-30b133b061b34f53895c9c7d325b54a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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