Chlorohydroquinone → 4-Dodecyloxybenzyl(4-hydroxy-2-chlorophenyl) ether

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Reaction Steps

In an aqueous solution of sodium hydroxide, 2.0 g of 4-dodecyloxybenzyl bromide synthesized in the same manner as described in Referential Example 17 was reacted under reflux with 1.0 g of 4-hydroxy-3-chlorophenol for 8 hours, the thus-obtained solution was put into ice-cooled hydrochloric acid, and the precipitate was recovered by filtration, washed, dried and purified by the silica gel column chromatography to obtain 0.8 g of 4-dodecyloxybenzyl(4-hydroxy-2-chlorophenyl) ether.

Provenance & Evidence