Stearoyl chloride → HCID 15077447, compound

HRID 1650661Notes

Reaction equation

HRID 1650661 reaction equation
[CH3:1][C:2]1[N:3]([CH2:7][CH2:8][CH:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)[CH:4]=[CH:5][N:6]=1.C(Cl)(=O)CCCCCCC[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32].[C:35](Cl)(=[O:40])[C:36]([CH3:39])([CH3:38])[CH3:37]>>[O:40]=[C:35]([N:12]1[CH2:13][CH2:14][CH:9]([CH2:8][CH2:7][N:3]2[CH:4]=[CH:5][N:6]=[C:2]2[CH2:1][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH3:23])[CH2:10][CH2:11]1)[C:36]([CH3:39])([CH3:38])[CH3:37]

Participants

4

Reactant 3

HCID 8212Stearoyl chlorideHCID 62493Pivaloyl chlorideHCID 64846854-[2-(2-Methyl-1H-imidazol-1-yl)ethyl]piperidine2×

Product 1

HCID 15077447HCID 15077447, compound

Procedure

Following essentially the last step of the procedure for preparing the compound of Example 1, and using in place of 4-[2-(2-methyl-1H-imidazol-1-yl)ethyl]piperidine and stearoyl chloride, approximately equivalent amounts of the compound of Example (5A) and pivaloyl chloride, respectively, the title compound was obtained as an oil.

Sources & evidence

ORD record
ord-cf6c9a0461c04d5ba68f971a5fd0bc23
Source dataset
uspto-grants-1990_05
Patent number
US04925851

Reaction notes

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