Stearoyl chloride → HCID 15077448, compound

HRID 1650662Notes

Reaction equation

HRID 1650662 reaction equation
[CH3:1][C:2]1[N:3]([CH2:7][CH2:8][CH:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)[CH:4]=[CH:5][N:6]=1.C(Cl)(=O)CCCCC[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]CC.[C:35](Cl)(=[O:41])[CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]>>[O:41]=[C:35]([N:12]1[CH2:13][CH2:14][CH:9]([CH2:8][CH2:7][N:3]2[CH:4]=[CH:5][N:6]=[C:2]2[CH2:1][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH3:21])[CH2:10][CH2:11]1)[CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]

Participants

4

Reactant 3

HCID 8212Stearoyl chlorideHCID 67340Hexanoyl chlorideHCID 64846854-[2-(2-Methyl-1H-imidazol-1-yl)ethyl]piperidine2×

Product 1

HCID 15077448HCID 15077448, compound

Procedure

Following essentially the last step of the procedure for preparing the compound of Example 1, and using in place of 4-[2-(2-methyl-1H-imidazol-1-yl)ethyl]piperidine and stearoyl chloride, approximately equivalent amounts of the compound of Example (5A) and hexanoyl chloride, respectively, the title compound was obtained as a liquid, b.p. 167°-170° C.

Sources & evidence

ORD record
ord-a4c49c2f40b64c0ab66095707ca5677a
Source dataset
uspto-grants-1990_05
Patent number
US04925851

Reaction notes

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