HCID 23052320, compound → HCID 23052289, compound

Participants

Reaction Steps

1.75 g. (5.5 mMole) 2-(4-pyridyl)-3,3-dimethyl-5-(3-oxo-2,3,4,5-tetrahydro-6-pyridazinyl)-3H-indole (see Example 2 b)) was stirred with 25 g. manganese dioxide in 260 ml. dioxan for 20 hours at 90° C. The reaction mixture was subsequently filtered off with suction, the residue stirred up with methanol/methylene chloride and the combined filtrates evaporated to dryness. After crystallisation from methanol, there was obtained 1 g. (58% of theory) of the title compound; m.p. 305°-307° C.

Provenance & Evidence