Water → HCID 54452095, compound

HRID 1650728Notes

Reaction equation

HRID 1650728 reaction equation
O.[OH-].[Na+].[CH3:4][C:5]([C:7]1([Cl:10])[CH2:9][CH2:8]1)=[O:6].[Cl:11][C:12]1[CH:19]=[CH:18][C:15]([CH:16]=O)=[CH:14][CH:13]=1>C(O)C>[Cl:11][C:12]1[CH:19]=[CH:18][C:15]([CH:16]=[CH:4][C:5]([C:7]2([Cl:10])[CH2:9][CH2:8]2)=[O:6])=[CH:14][CH:13]=1

Participants

6

Reactant 4

HCID 962WaterHCID 77264-ChlorobenzaldehydeHCID 14798Sodium HydroxideHCID 13214306Ethanone, 1-(1-chlorocyclopropyl)-

Product 1

HCID 54452095HCID 54452095, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

50 ml of water and 10 pellets of solid sodium hydroxide are added at room temperature to a mixture of 0 g (0.5 mol) of 1-chlorocyclopropyl methyl ketone, 70 g (0.5 mol) of 4-chlorobenzaldehyde and 250 ml of ethanol. The mixture is stirred at room temperature for 16 hours. The precipitated solid is then filtered off with suction. In this manner, 108.5 g (89% of theory) of 1-chlorocyclopropyl 4-chlorophenylethenyl ketone are obtained in the form of a solid substance of melting point 92° C.

Workup

  1. filtrationThe precipitated solid is then filtered off with suction

Sources & evidence

ORD record
ord-d98639e5918147b185890e5423a8c0dd
Source dataset
uspto-grants-1990_05
Patent number
US04925865

Reaction notes

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