Formic Acid → HCID 14344237, compound

Participants

Reaction Conditions

Reaction Steps

32.6 g (0.22 mole) of an approximately 50% strength aqueous glyoxylic acid solution were added dropwise to 14.9 g (0.10 mole) of 2,6-diethylaniline and 100 ml of formic acid at room temperature, with gentle warming. The mixture was stirred at 70° C. for 1 hour, with vigorous evolution of gas, the formic acid was distilled off up to an internal temperature of 120° C., the mixture was allowed to cool and was poured onto water and the solid was filtered off with suction and dired. 21.8 g of N-(2,6-diethylphenyl)-N-formylglycine of melting point 139-41° C. were obtained.

Provenance & Evidence