Hydrochloric Acid → Triazole,3-nitro-1-(2-fluoro-3-hydroxy)propyl-

Participants

Reaction Steps

2N-HCl was added to 420 mg (1.81 mmol) of 1-(2'fluoro-3'-acetoxypropyl)-3-nitro-1,2,4-triazole and stirred overnight at room temperature. Then, the reaction solution was concentrated and subjected to isolation and purification by silica gel column chromatography to give 230 mg of 1-(2'-fluoro-3'-hydroxypropyl)-3-nitro-1,2,4-triazole.

Provenance & Evidence