HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Methoxyimino-3-oxobutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tert-butyl 2-methoxyimino-3-oxobutyrate | HCID 54110352 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Methoxyimino-3-oxobutyric acid | HCID 54183495 | 95.8% |
Reaction Steps
Tertiary-butyl 2-methoxyimino-3-oxobutyrate (805 g) was dissolved in 2.8 liters of methylene chloride. Hydrogen chloride (210 g) was blown into the solution at 3° to 6° C. over 8 hours. Then, the resultant mixture was allowed to stand at 5° C. for 15 hours. The supernatant was concentrated to dryness to give 556 g of 2-methoxyimino-3-oxobutyric acid as a crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04927964 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-f754cb83fa5841ae83ec40d69a34540c |
| Source note | uspto-grants-1990_05 |