N-aminobenzenecarbothioamide → HCID 13773249, compound

HRID 1651438Notes

Reaction equation

HRID 1651438 reaction equation
[C:1]1([C:7]([NH:9][NH2:10])=[S:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:11]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)(=[O:14])[CH:12]=O>C(O)C>[C:1]1([C:7]2[S:8][CH:12]([C:11]([O:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[O:14])[NH:10][N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 3361911N-aminobenzenecarbothioamideHCID 11008258Benzyl glyoxylate

Product 1

HCID 13773249HCID 13773249, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of benzenecarbothioic acid hydrazide (2g) and benzyl glyoxylate (2.6g) in ethanol (5ml) was stirred at room temperature for 18 hours under nitrogen. The solvent was removed by evaporation and the residue was flash chromatographed to yield the sub-title product (3.5g) as a beige solid.

Workup

  1. customThe solvent was removed by evaporation
  2. customchromatographed

Sources & evidence

ORD record
ord-ca4f184d203a4ae0bd60f177337baaad
Source dataset
uspto-grants-1990_05
Patent number
US04927822

Reaction notes

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