Hydrochloric Acid → HCID 13773286, compound

HRID 1651454Notes

Reaction equation

HRID 1651454 reaction equation
[CH2:1]([O:3][C:4]([C@@H:6]([NH:15][C@H:16]([C:18]([N:20]1[N:24]=[C:23]([C:25]2[CH:30]=[CH:29][C:28]([S:31][CH3:32])=[CH:27][CH:26]=2)[S:22][C@H:21]1[C:33]([O:35]C(C)(C)C)=[O:34])=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:5])[CH3:2].Cl>C(OCC)C>[CH2:1]([O:3][C:4]([C@@H:6]([NH:15][C@H:16]([C:18]([N:20]1[N:24]=[C:23]([C:25]2[CH:26]=[CH:27][C:28]([S:31][CH3:32])=[CH:29][CH:30]=2)[S:22][C@H:21]1[C:33]([OH:35])=[O:34])=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13773284HCID 13773284, compound

Product 1

HCID 13773286HCID 13773286, compoundYield 11.1%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of the product (1.0 g) from step (f) in dry diethyl ether (50 ml) was saturated with hydrogen chloride for 3 hours. The solvent was evaporated and the residue was purified by chromatography to give the title compound (0.1 g) as a pale yellow solid. mp 163°-164°

Workup

  1. customThe solvent was evaporated
  2. customthe residue was purified by chromatography

Sources & evidence

ORD record
ord-5f8ffb17d12f4278832f7a03715a21a7
Source dataset
uspto-grants-1990_05
Patent number
US04927822

Reaction notes

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