反应详情

To stirred ammonium hydroxide (150 ml) was added dropwise 5-methoxycarbonylthieno[2,3-b]thiophene-2-sulfonyl chloride (11.58 g. 39.02 mmoles) dissolved in acetone (140 ml). After the addition was complete, the solution was stirred for 30 minutes. The reaction was worked up by evaporating the ammonia and acetone in vacuo. The crystals were collected and dried (9.66 g.) (89%). Recrystallization from nitromethane gave 7.02 g. mp 219°-220° C.

1. additionAfter the addition
2. customby evaporating the ammonia and acetone in vacuo
3. customThe crystals were collected
4. customdried (9.66 g.) (89%)
5. customRecrystallization from nitromethane
6. customgave 7.02 g