Sodium → HCID 131715136, compound

HRID 1651638Notes

Reaction equation

HRID 1651638 reaction equation
[OH:1][NH:2][C:3]([C:5]1[S:9][C:8]2[CH:10]=[C:11]([O:16][CH3:17])[C:12]([O:14][CH3:15])=[CH:13][C:7]=2[CH:6]=1)=[O:4].[Na:18]>CO>[OH2:1].[Na:18].[OH:1][NH:2][C:3]([C:5]1[S:9][C:8]2[CH:10]=[C:11]([O:16][CH3:17])[C:12]([O:14][CH3:15])=[CH:13][C:7]=2[CH:6]=1)=[O:4]

Participants

4

Reactant 2

HCID 5360545SodiumHCID 23050230HCID 23050230, compound

Product 1

HCID 131715136HCID 131715136, compoundYield 185.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

N-Hydroxy-5,6-dimethoxy-benzo[b]thiophene-2-carboxamide (2.5 g) was added to a stirred solution of sodium metal (0.227 g) in methanol (55 ml). After 15 min. the solution was evaporated to dryness and the residue crystallised from methanol:ether to give N-hydroxy-5,6-dimethoxy-benzo[b]thiophene-2-carboxamide sodium salt monohydrate (2.7 g), m.p. 170°-185° C. (decomp.).

Workup

  1. customAfter 15 min. the solution was evaporated to dryness
  2. customthe residue crystallised from methanol

Sources & evidence

ORD record
ord-fc45a7dffb054968a5417937e98c9d68
Source dataset
uspto-grants-1990_05
Patent number
US04929636

Reaction notes

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