HRID1653611

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67755

Iodotrifluoroethylene

C2F3I

HCID13931028

未命名化合物

PRODUCTS

生成物

结构：CCCC1CCC(C2CCC(c3ccc(C(F)=C(F)F)cc3)CC2)CC1

HCID20080204

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23994

Zinc

结构：c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

催化剂HCID178418397

未命名化合物

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

A mixture of 5.0 g (77 mmol) of zinc powder, 50 ml of THF and 13.5 g (65 mmol) of trifluoroiodoethylene is stirred overnight, initially with ice cooling, later at room temperature. 20.5 g (50 mmol) of 1-iodo-4-[4-(4-propylcyclohexyl)cyclohexyl]benzene and 1.1 g-of tetrakis(triphenylphosphine)palladium are then added.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9e3c7aec233d464aa7cfacce147fef7c
来源数据集: uspto-grants-1995_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05403512
来源说明: uspto-grants-1995_04

反应 SMILES

[F:1][C:2]([F:6])=[C:3]([F:5])I.I[C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][CH:17]([CH:20]3[CH2:25][CH2:24][CH:23]([CH2:26][CH2:27][CH3:28])[CH2:22][CH2:21]3)[CH2:16][CH2:15]2)=[CH:10][CH:9]=1>[Zn].C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1COCC1>[CH2:26]([CH:23]1[CH2:22][CH2:21][CH:20]([CH:17]2[CH2:18][CH2:19][CH:14]([C:11]3[CH:12]=[CH:13][C:8]([C:3]([F:5])=[C:2]([F:6])[F:1])=[CH:9][CH:10]=3)[CH2:15][CH2:16]2)[CH2:25][CH2:24]1)[CH2:27][CH3:28]