HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Benzyloxy-pyrid-2-ylsulfonamide → 3-Hydroxypyridine-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Benzyloxy-pyrid-2-ylsulfonamide | HCID 19957934 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Hydroxypyridine-2-sulfonamide | HCID 19957938 | — |
Reaction Steps
A solution of 263.7 g of 3-benzyloxy-pyrid-2-ylsulfonamide in 2.5 l of methanol is hydrogenated with the addition of 26 g of 5% Pd/C catalyst. After 23.8 l of hydrogen have been absorbed, the catalyst is filtered off. After evaporation of the methanol, 3-hydroxypyrid-2-ylsulfonamide remains in the form of a crystalline mass. Melting point 162°-164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05403814 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-eb95c2fac7874c788366ee6643fedcc4 |
| Source note | uspto-grants-1995_04 |