Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(4-Methoxyphenoxy)butanoic acid | HCID 249649 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 13574374 | HCID 13574374 | — |
Reaction Steps
Benzene (70.0 cc) and 14.0 grams of γ-(p-methoxyphenoxy)butyric acid were agitated with water cooling and 5.74 cc of thionyl chloride was added dropwise. Subsequently, the mixture was agitated for 10 minutes at an internal temperature of 60° C. After the reaction had been completed, the reaction mixture was cooled and transferred to a separate flask and the solvent and excess thionyl chloride were removed in a rotary evaporator. γ-(p-Methoxyphenoxy)butyric acid chloride was obtained as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05403811 |
|---|
| Source dataset | uspto-grants-1995_04 |
|---|
| ORD ID | ord-5da6f7e9126745c5bd3491b522276710 |
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| Source note | uspto-grants-1995_04 |
|---|
