HCID 15239970, compound → HCID 15239971, compound

Participants

Reaction Steps

1.12 g (2 mmol) of methyl 3-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[N-(2-phenoxy)ethyl-N-benzyloxycarbonylamino]picolinate was catalytically reduced in 30 ml of methanol in the presence of 1 g of palladium carbon (10%). The catalyst was filtered off, and the filtrate was distilled under reduced pressure at a low temperature of not higher than 40° C., and the residual oily product was purified by column chromatography to obtain the desired product as colorless transparent oily product.

Provenance & Evidence