HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 146422-39-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Aminonicotinic acid | HCID 72930 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 146422-39-1 | HCID 70342450 | 103.5% |
Reaction Steps
2-Aminonicotinic acid (0.912 g, 6.6 mmol) was dissolved in 90% methanol (137 ml) and conc. HCl (3.5 ml, 40 mmol) was added. The solution was hydrogenated over PtO2 (200 mg) in a Parr shaker apparatus at room temperature and 29 psig for 2 hours. Filtration and evaporation gave 1.22 g (100%) oily product identified by ir 3300-2500, 1724 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05403845 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-8f8ee3086af5403cb541c9e84ed1ae4f |
| Source note | uspto-grants-1995_04 |