Hydrochloric Acid → HCID 70342222, compound

Participants

Reaction Steps

2-Aminopyridine-6-carboxylic acid (Farinaco. Ed. Sci. 1959, 14, 594; 2.01 g, 14.5 mmol) was dissolved in 90% methanol (200 ml) and conc. HCl (7.2 ml, 87.4 mmol) was added. The solution was hydrogenated over PtO2 (340 mg) in a Parr shaker apparatus at room temperature and 29 psig for 2 hours. Filtration and evaporation gave 2.08 g (80%) crude white crystals identified as the product by 300 MHz nmr and ir 1724 cm-1.

Provenance & Evidence