1,5-Dibromopentane → HCID 19972716, compound

HRID 1653788Notes

Reaction equation

HRID 1653788 reaction equation
BrCC[CH2:4][CH2:5][O:6][C:7]1[C:16]2[O:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:13]([CH3:23])[C:12](=[O:24])[C:11]=2[CH:10]=[CH:9][CH:8]=1.[Br:25][CH2:26][CH2:27][CH2:28]CCBr>>[Br:25][CH2:26][CH2:27][CH2:28][CH2:4][CH2:5][O:6][C:7]1[C:16]2[O:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:13]([CH3:23])[C:12](=[O:24])[C:11]=2[CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 81001,5-DibromopentaneHCID 19972647HCID 19972647, compound

Product 1

HCID 19972716HCID 19972716, compound

Procedure

This compound was prepared by the method described for the preparation of Intermediate XVI, but using 1,5-dibromopentane in place of 1,4-dibromobutane and purifying the crude product by column chromatography on silica gel (elution with dichloromethane:ethyl acetate 99:1) m.p. 75°-76° C., after rinsing with petroleum ether:diethyl ether 30:4.

Workup

  1. customThis compound was prepared by the method
  2. custompurifying the crude product by column chromatography on silica gel (elution with dichloromethane:ethyl acetate 99:1) m.p. 75°-76° C.
  3. washafter rinsing with petroleum ether:diethyl ether 30:4

Sources & evidence

ORD record
ord-5b38ddfa6d71440281de5db3411101d1
Source dataset
uspto-grants-1995_04
Patent number
US05403842

Reaction notes

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