Dimethyl Sulfoxide → 4-benzyloxy-3-[(4-(N-methyl-N-(1-ethoxycarbonyl-1-methylethyl)amino)-6-(3-(1-methylimidazolin-2-yl)phenoxy)-3,5-difluoropyridin-2-yl)oxy]benzonitrile
Reaction equation
[C:50](=[O:51])([O-:52])[O-:53].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:17][c:18]2[n:19][c:20]([F:36])[c:21]([F:35])[c:22]([N:25]([C:26]([CH3:27])([CH3:28])[C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH3:34])[c:23]2[F:24])[cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]1.[CH3:37][N:38]1[C:39]([c:43]2[cH:44][c:45]([OH:49])[cH:46][cH:47][cH:48]2)=[N:40][CH2:41][CH2:42]1.[CH3:57][S:58]([CH3:59])=[O:60].[CH3:61][CH2:62][O:63][C:64](=[O:65])[CH3:66].[Cs+:54].[Cs+:55].[OH2:56]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:17][c:18]2[n:19][c:20]([O:49][c:45]3[cH:44][c:43]([C:39]4=[N:40][CH2:41][CH2:42][N:38]4[CH3:37])[cH:48][cH:47][cH:46]3)[c:21]([F:35])[c:22]([N:25]([C:26]([CH3:27])([CH3:28])[C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH3:34])[c:23]2[F:24])[cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-bb7b6d1b158e4376a29491b52fc1611e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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